Protein Tyrosine Phosphatases: Methods 4nd Protocols
Rafael Pulido, &quotProtein Tyrosine Phosphatases: Methods 4nd Protocols&quot
English | 2016 | 402 Pages | ISBN: 1493937448 | EPUB | 5 MB
This book provides coverage, methodology, 4nd lab08rat08ry protocols on the m08re essential aspects of protein tyrosine phosphatase (PTP) function 4nd regulation, including the use of st4ndardized in vitro functional assays, suitable cell systems, 4nd animal 4nd micro08rganism models. Chapters covering state-of-the-art technical approaches suitable to decipher the physiologic roles of PTPs, 4nd their involvement in tissue-specific functions, are also included, which will be of utility f08r both newcomers 4nd experienced researchers in the field of tyrosine- 4nd phosphoinositide- phosph08rylation/dephosph08rylation. Written in the highly successful Methods in Molecular Biology series f08rmat, chapters include introductions to their respective topics, lists of the necessary materials 4nd reagents, step-by-step, readily reproducible lab08rat08ry protocols, 4nd tips on troubleshooting 4nd avoiding known pitfalls. Auth08ritative 4nd practical, Protein Tyrosine Phosphatases: Methods 4nd Protocols aims to aid researchers in better defining the common 4nd individual features of the PTP family members 4nd translating this knowledge 1n8t0 PTP-based therapy f08r human disease.